The Swissman Xtreme Triathlon features 3 tough mountain passes on the bike and lots of climbing during the run, but this year the weather forced the swim to be cancelled. The official video from the event however is impressive just the same and folks who participated found the race plenty tough and cold.
The Gotthard Pass is the first tough climb that has to be navigated, and it is followed by the Furkapass and the Grimselpass.
How about this as a course profile? The race features a total ascent of 5,400 meters.